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5 kbar (see Sassaroli et al
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METHODSThree simulations of 10 ns at 300 K, 1 atm, were carried out for three different systems in explicit solvent: free HIV-1 gp120 with the truncated LAI strain sequence (SWISS-PROT accession number P03377; 346 residues and 29,047 water molecules), free CD4 (99 residues of the D1 domain and 7768 water molecules), and their complex (445 residues and 30,242 water molecules)
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, unequal elevations) which necessitated that the data be fitted with a parallel-line multiple linear regression model (Fig
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--Pharmaceutical Sciences* DISTRICT OF COLUMBIAHoward University School of Pharmacy M
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