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. Hence, with reasonable SNR, even one or two millimolar concentrations appear to be detectable noninvasively on a cellular level, rendering localized spectroscopy with Xenopus oocytes an attractive methodology to noninvasively determine the permeability of a cell for specific drugs, especially since the membrane of amphibian oocytes frequently serves as a broader membrane model (45-49)
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. Wijmenga**Department of Medical Biochemistry and Biophysics, and [dagger] Department of Molecular Biology, University of Umeå, S-901 87 Umeå, SwedenSubmitted November 8, 2004, and accepted for publication May 4, 2005
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. During interphase, DNA exists in a rather compact state (compared to the elongated state in aqueous solution) and extra compaction is required during mitosis to realize cell division
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. These results, and those using CPM-PLCβ gave similar volume changes which were approximately twice as high as that seen for the associations on membrane surfaces
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. ApoA-1 and apoA-2 comprise ~70% and 20% of the total HDL protein content, respectively
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. Such unspecific effects may contribute to morphological differences in any protein's amyloid samples induced at high temperature
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. DLS was used to measure particle size as a function of time
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. FRET histogram simulationsFRET histogram simulation routines were written in Matlab (The Math-Works, Natick, MA)
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. The rate constants were expressed in units of an experimental reference time, the average burst duration, as discussed later
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. If this is indeed the case, then our task reduces to estimating the impact of RP on price
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. These differences could be due to the thermophilic nature of EIC^sup tt^
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