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Molecular graphics were created with PyMOL (38)
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Fluorescence experiments at pH 7 and 9 showed a sigmoidal transition with T^sub m^ = 311 ± 4 K (Fig
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Shobini Jayaraman, Donald L
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In this case, the slow search for a specific binding site in d = 3 is substituted for a much more rapid diffusive search in d = 1 (along the DNA) by nonspecific binding of the repressor proteins
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Despite the limited sampling time of 10 ns, the theoretically derived changes in configurational entropy are in fair agreement with the experimentally determined data
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This suggests that, for these sets, sufficient sampling of conformational space has been achieved and that relatively precise conformational entropy differences between the two states can be obtained, although the values for the V3 loop should be taken with caution
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Briefly, fluorescence measurements were carried out using a home-built laser confocal microscope system, based around an Axiovert 200 microscope (Zeiss, Thornwood, NY)
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In contrast, the specifically-docked conformation (exemplified by the WT 4WJ) is stabilized by an extensive hydrogen bond network (14 hydrogen bonds in all (Rupert and Ferre-D'Amare, 2001)), prolonging the lifetime of this state
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Of the 30 cases of reactive mesothelial proliferation, 16 were biopsies from pleuropulmonary specimens (6 lungs with overlying pleura and 10 pleural specimens) and 14 were cell blocks from pleural effusions
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"We know that an imprecise definition of AMP, especially if publicly posted, will be misleading to state Medicaid directors and others who will use this as a reference point for setting pharmacy reimbursement," said McClellan
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The SF12 was used because it is a widely used HRQOL measure and has been reported to have excellent reliability and validity (Ware et al
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population over age 21 - visited a casino last year, averaging a trip about once every two months or 5
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Because of these limitations, the probabilistic models may not be general enough to ascribe odds and explain play
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