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For comparison, the δ values calculated from native structures are also shown as open circles
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The difference in configurational entropy between two molecular conformations a and b can be estimated as ΔS = k^sub B^/2 ln(detσ^sub a^/detσ^sub b^), where σ^sub a^ and σ^sub b^, are the covariance matrices of atomic positional fluctuations of the two conformers and k^sub B^ is Boltzmann's constant
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Moreover, the four-way junction was uniquely able to fold to a similar compact structure even in the absence of specific loop-loop docking interactions
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All SL constructs show just a single peak in the FRET efficiency histograms, with no distinct docked peak, as expected (Fig
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8 × 10^sup 3^ s^sup -1^, respectively
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