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8 million, a staff of some 150, a 200-member board of councilors, and hundreds of donors, including not only individuals and foundations, but the U
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The large-scale fluctuations that give rise to the contact density maps shown in Fig
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For small x, the discrepancy is even more pronounced
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SWISS-MODEL and the Swiss-PDB viewer: an environment for comparative protein modelling
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Large-amplitude thermal fluctuations, requiring adequate protein hydration, have been shown to be mandatory for the function of bacteriorhodopsin, the light-driven proton pump in the purple membrane of Halobacterium salinarum (7)
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Denaturation of proteins, whether to a totally unfolded conformation or to a partially unfolded molten globule, has been shown to be reflected in increased atomic thermal motions relative to the native state by several techniques, including NMR (Idiyatullin et al
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6 and 7, it is also evident that a higher solder temperature improves wettability as the contact angle decreases for all fluxes
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Looking at the first portion of the righthand side of Eq
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5, C and D) and shorter fluorescence lifetimes (data not shown) reveal Trp to ANS and Bis-ANS fluorescence resonance energy transfer both in the native and misfolded states, indicating that the Tips and the probes are in close proximity (Conrad and Brand, 1968)
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The negative slope in the heating and cooling curves in Fig
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, 2002), and the DSC data show only the lipid phase transition but lack the high-temperature peak because of the low unfolding enthalpy of this small protein
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This suggests that the aggregation process is essentially completed after 1 h at 70°C
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Folding dynamics of the B1domain of protein G explored by ultrarapid mixing
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An alternative, machining with "minimum quantity lubricant," or MQL, is gaining acceptance as a cost-saving and environmentally friendly option in place of some wet machining processes
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It is fascinating to think that nature custom-made proteins so that, when digested by gut enzymes, useful bioactive peptides result
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