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. CD measurements suggested that unfolding of GR was complete at 7 M GdnHCl, a result that was consistent with the iodide quenching data
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. Equation of state calculations by fast computing: machines
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. Transmission values varied from 0
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. The binding of soman to HuBChE via a single covalent bond (plus a salt bridge between a negatively charged oxygen on the phosphoryl moiety, and the protonated imidazole ring of His-438) may explain why it does not noticeably affect global HuBChE molecular dynamics
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. BD=body depth; BL=body length;ED=eye diameter; HD=head depth; HL=head length; PAL=preanal length
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. To estimate errors, several independent simulations could be performed and compared
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. Ribozyme constructs were prepared in 50 mM Tris/HCl (pH 7
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. In striking contrast, neither the 2WJ nor the 3WJ ribozymes can populate such a high-FRET state in the absence of loop A
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. CMS administrator Mark McClellan told independent and small-chain pharmacy operators last month that the agency would suspend for now the adoption of a controversial new Medicaid pharmacy reimbursement formula that pharmacists fear would severely undercut their already slim profit margins
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. The histogram of interresidue contacts can be plotted as a contact density map and the results are shown in the top row of Fig
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.The authors thank Jacques Colletier for useful discussions on cholinesterase biochemistry as well as the IN16 instrumental team (Bernhard Frick, Thilo Seydel, and Matthias Elender) and the IN13-CRG team (Marc Bée, Francesca Natali, and Sebastien Vial) at the Institute Laue-Langevin, Grenoble, France
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. All of these monocations collapsed DNA into globules and the concentrations of monovalent salts needed to induce DNA compaction varied greatly
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. The fluorescence intensity of the different probes in the presence of the unfolded monomer state is shown in Fig
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. Alternately, it is possible that multiple Gβ86-105 peptides bind to the enzyme giving the same overall volume change
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