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These have included--to name just two examples--his letter-writing campaign in 1990 to members of the United Nations Security Council, in an effort to thwart the Bush I coalition that fought the first Gulf War against Saddam Hussein; and his 1994 trip to North Korea, where he proposed to the dying tyrant Kim Il Sung a deeply flawed nuclear-freeze deal that may well have helped Kim's son consolidate power and develop ICBMs and atomic bombs
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. The song that consolidated Cash's "outlaw" reputation is "Folsom Prison Blues" (1956), sung from the point of view of a jailed killer listening to a distant train whistle
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. Thermodynamic data on the conformational stability of proteins can be obtained using several chemical or physical perturbants, including chaotropic agents (guanidine hydrochloride, urea), hydrostatic pressure, and temperature
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. A local length scale spans five- to nine-residue stretches over which sequence-specific spatial correlations decay
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. CFTR deficiency also alters the epithelial response to apoptotic cells, resulting in the enhanced release of the neutrophil chemoattractant IL-8
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. The linewidth of the diminazene peak in the nucleus is initially about twice as broad as that of aceturate and approaches the latter over time, whereas the linewidths of both molecules in the medium are nearly identical
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. The remaining residues (see Table 1) show a weak decrease in exchange rate upon change in temperature (f [asymptotically =] 0
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. Therefore, the difference between DCVJ and ThT is that ThT does not fluoresce in the presence of protofibrillar amyloid of TTR at pH 3
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. Despite the large amounts of ACYI that exist in mammalian kidney and liver, the reactivation of ACYI is particularly difficult in vitro (19-21), which suggests that the folding of ACYI in vivo might be assisted by the possible intracellular molecular chaperones and/or osmolytes
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