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. The event, which was held on June 25th at the Bridgehampton Tennis & Surf Club, was highlighted by a silent auction featuring specially commissioned hand-painted ceramic plates and a select live auction offering original works by prominent names in art, design and entertainment
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. A schematic diagram with the primary structure of the glycan is shown in Fig
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. 1 M^sup -1^) similar to those measured in isolated EI^sup SC^ (Table 1), and smaller when PEP (1
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. In EI^sup sc^, a single peak was observed in CD and DSC experiments, but in the pH range where the thermal transitions could be followed (pH 7-9), two different peaks were not observed; further, the T^sub m^ of the sole transition observed was pH-indcpendent between pH 7 and 9 (Fig
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. Linear regimes are hard to identify
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. A homodimeric peptide corresponding to the complete SEF2-1 basic sequence, henceforth called SEF2-1mp, was chosen as a good model system for NMR studies of the interactions between bHLH proteins and Ca^sup 2+^/CaM
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. The kinetic CD data were also recorded in denaturant-jump experiments with the disks
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. We formally tested this hypothesis by estimating the parameters of equation (1) (which are displayed along with other parameter estimates in an online-only appendix) and, using these estimates, testing the hypotheses that equations (2) and (3) were both equal to 0
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. The aromatic chromophore 1-anilino-8-naphthalene sulfonate (ANS) is feebly fluorescent in water, but its spectrum is blue shifted and its intensity is dramatically increased in nonpolar solvents or when it binds to nonpolar sites of proteins (4,5; for a general review, see Slavik (6))
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. As the maximum size of a voxel that allows for intracellular spectroscopy in a Xenopus oocyte would be about (600 µm)^sup 3^, the same SNR as in our experiments could be achieved if the drug concentration were to be reduced by a factor of 27 (i
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