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Glycoproteins: what are the sugar chains for? In Proteins: Form and Function
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This conclusion has been reached through quantitative studies of the scaling of hydrodynamic radii (46) and radii of gyration (11,47) with chain length under harshly denaturing conditions
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These interactions will be determined by the specific sequence or, more precisely, by native-state topology
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However, quenching experiments and proteolysis patterns suggest conformational changes in the presence of PEP; furthermore, the thermal stability of EI^sup SC^ was modified depending on the effector added
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The El^sup sc^ modeled structure We have modeled the EI^sub sc^ structure to find a framework in which our experimental results could be adequately explained
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(16) This exposure of PS by apoptotic cells is of particular interest, because it induces membrane ruffling and efferocytosis, and it has been implicated in many of the immunomodulatory effects associated with efferocytosis (more below)
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Backbone dynamics of a free and phosphopeptide-complexed Src-2 homology domain studied by ^sup 15^N relaxation
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, 2002), and the DSC data show only the lipid phase transition but lack the high-temperature peak because of the low unfolding enthalpy of this small protein
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Off the coast of Oregon, widow rockfish (Sebastes entomelas) have exhibited increased absolute fecundity, and more importantly have increased relative fecundity, with age (Boehlert et al
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These data were fitted with a cooperative binding model, and the resulting fits are shown as solid lines in Fig
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3-6 Here, we report our experience with the role of the autocrine loop using TGF-[alpha] and EGFR immunohistochemistry in formalin-fixed tissues from malignant pleural mesotheliomas and reactive mesothelial proliferations
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Streptavidin-Biotin complex (Dako A/S) was applied for 30 minutes, followed by a substrate solution containing 0
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40 reduction in Pharmacare reimbursement prices that eventually accrued after the introduction of Type 2 RP (Figure 2)
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. Besides the shift of transition temperatures caused by different heating rates, pronounced differences in the λ^sub max^-values for the unfolded states are visible in Fig
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. Due to the complexity of the investigated proteins (multitryptophan proteins in an ensemble of structurally heterogeneous unfolded states) a quantitative relation between λ^sub max^-values and the extent of aggregation or the compactness of the unfolded state cannot be given
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