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This indicates that subtle conformational changes are induced by low concentrations of GdnHCl (The existence of partially folded intermediate states in the unfolding of GR is indicated by a comparison of fluorescence spectral shift, anisotropy, iodide quenching, and CD data as a function of GdnHCl concentration
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0 K/min from 20°C in 90°C
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This is referred to as U'
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How to small single-domain proteins fold? Fold
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0 The scan rates were 30 K/h
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lowest line) could be titled to a two-state mechanism, with T^sub m^ = 332 K (Table 3)
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The results of the trypsin digestion and quenching experiments qualitatively agree, indicating that EP suffers conlbrmational changes upon binding to PEP
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After 2 h, only very small aggregates (400 h), the protofibrils have increased in length to 100-200 nm, and the spherical clusters have decreased in size to 20-30 nm in diameter (Fig
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The light-scattering cooling curves recorded at faster rates (1
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In addition, our previous MD analysis of the intermolecular hydrogen bonding shows that all these residues, except CD4-K22, form only marginally stable intermolecular hydrogen bonds
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ResultsOvarian developmentBlack rockfish off Oregon exhibited group-synchronous oocyte development; and females extruded only one brood of larvae per year (Fig
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The immunoglobulin subclass of monoclonal antibodies was determined according to the directions of the mouse monoclonal antibody isotyping kit (Amersham Pharmacia Biotech Co
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, 2000; Russell et al, 2002a; Zhuang et al, 2002)
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-- Beginning today, retail drug has two powerful women at the helm, one on land and one online
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Type 2 RP had virtually no effect on drug prices although the delisting of the various NSAIDs in November 1996 did coincide with a marked drop in the second line restricted drug prices
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Fresh off a six-hole golf fix in sweltering 106-degree weather, Don Barden seems to enjoy the serenity of the moment
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Just as there are underage drinkers of alcohol, there are the underage who frequent casinos and create a regulatory problem for the industry, and occasionally personal problems for themselves
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