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. As a first step in this direction, we measured the thermal unfolding transition of α-amylases in the presence of NDSB, which is known to be an effective agent to prevent aggregation of thermal unfolded proteins (32-34)
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. 8) is structurally and catalytically very similar to AChE (21)
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. Consequently, our experimental data are at variance with the MD simulations of Tara et al
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. Similarly, there does not appear to be any effect of the extent of glycosylation on the kinetic characteristics of either Drosophila (63) or human (64) AChE
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. It is tempting to speculate that the CaM dimer opening-closing process is coupled with the CaM:SEF2-1mp interaction, i
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. Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells
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. Determination of a transition state at atomic resolution from protein engineering data
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. The immunoglobulin subclass of the monoclonal antibodies was determined by observing the positions of bands that appeared on the stick
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. Total inventory scores were used in this study
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. The mean physical component (PCS 12) HRQOL score for the entire sample was 51
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. However, when asked about their attitude toward the future usefulness of the advice, an interesting pattern emerged
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