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. The Mn^sup 2+^ and Ca^sup 2+^ concentrations used were 5 mM in all the experiments unless specified otherwise
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. Time-resolved fluorescence anisotropy decay of ANS was shown to be a useful tool for giving further structural and kinetic information of the oligomeric aggregates
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. Circular dichroism spectroscopy and light scatteringCircular dichroism (CD) and light-scattering data were recorded using AVIV-215 spectrometer (AVIV Biomedical, Lakewood, NJ) with fluorescence accessory and Pelletier temperature control
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