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This leads us to further understanding of intermediate protein structures in the unfolding process
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Our approach is different because we use a single potential function to capture both local structure and nonlocal fluctuations
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4 K (Table 1); and 8 µM, T^sub m^ = 330
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(16) This exposure of PS by apoptotic cells is of particular interest, because it induces membrane ruffling and efferocytosis, and it has been implicated in many of the immunomodulatory effects associated with efferocytosis (more below)
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The C-terminal hydrophobic peptide was deleted by insertion of a stop codon to obtain a soluble protein, and the loop 103-136 was replaced by three histidines to facilitate purification
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Dynamics of Proteins and Nucleic Acids
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Condensed phases of DNA: structures and phase transitions
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Some characteristic traits of the mature amyloid fibrils are the tendencies to bend, twist, and agglomerate
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, 2003), α-synuclein (Khurana et al
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According to the polymeric paradigm (Fändrich and Dobson, 2002) of amyloidogenesis and the therein-implicated importance of backbone interactions, the more the native structure becomes distorted (and the protein backbone becomes exposed), the higher the chance that the protein steps onto the amyloidogenic pathway
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How to fold graciously
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, 2001, 2000) and applied to simulations of protein molten globule states (Schäfer et al
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Chemokine receptors as HIV-1 co-receptors: roles in viral entry, tropism, and disease
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Process for Making Single-Domain Magnetite CrystalsCrystals can be chemically pure and free of defects
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Scanning electron microscopy (SEM, Leica Stereoscan 430) and optical microscopy (OM, Olympus model OVM) were used to observe the morphology of toners and prints
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Complications and surgical errors are discussed practically and thoughtfully
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com president and chief executive officer Kal Raman has resigned to pursue other opportunities
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But limiting studies solely to blacks is equally amiss, claims Price
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, BiDil's manufacturer, has a monopoly on this patent, which was due to expire in 2007 but has now been extended to 2020 as a result of the drug-maker re-marketing BiDil for use among African Americans
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"Some have degrees, some do not
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More recent arrivals are the poker blogs shilling for their favorite sites, swooning over their favorite pros, and telling their stories about the hands that got away
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An interesting finding in the current study was that highly competitive participants, regardless of gender, reported higher levels of both intrinsic and extrinsic motivations than those who scored low in competitiveness
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Past studies have found that people tend to believe that a win is the result of skill, whereas a loss is the result of bad luck (e
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