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. Massey and Williams (1965) found 3
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. Thermal denaturation measurements Thermal denaturation experiments were carried out with a scanning rate of 50 K/h
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. Upon Ca^sup 2+^ binding, a conformational change enables it to interact with over 100 different target proteins, including transcription factors (for reviews, see Van Eldik and Watterson and others (6,7))
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.Suzanne ScarlataDepartment of Physiology & Biophysics, State University of New York at Stony Brook, New York 11794-8661Submitted November 4, 2004, and accepted for publication January 18, 2005
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